Mortality Surveillance and Minimally Invasive Tissue Sampling (MITS)



2018-07-08 00:00:00


Surveillance for deaths among under 5 children and stillbirths in Baliakandi sub-district, Rajbari and investigation of etiology: a CHAMPS study

 

Objectives:

Specifically, the program will have the following primary objectives:

1.    Identify under-5 deaths and stillbirths in Baliakandi sub-district of Rajbari district

·        Identify and enumerate all under-5 deaths and stillbirths in Baliakandi through:

                               i.      Hospital based mortality surveillance in Faridpur Medical College Hospital, Baliakandi Thana Health Complex;

                              ii.      Community-based mortality surveillance in Baliakandi sub-district, including reporting through call centre in Baliakandi

 

2.    Determine causes of under-5 deaths and stillbirths in the study population, including using MITS

·        Obtain MITS on as many under-5 deaths and stillbirths as possible and undertake histopathologic, bacterial culture, and molecular diagnostics of under-5 from Baliakandi

·        Obtain verbal autopsies and available maternal and clinical data on all eligible notified under-5 deaths and stillbirths in the study

·        Determine cause of death using all available histopathologic, bacterial culture, molecular diagnostics, and clinical, maternal and verbal autopsy data

3.    Estimating overall and cause-specific mortality rates (stillbirth and under-5) for Baliakandi sub-district of Rajbari district using data from mortality surveillance and cause of death determination, and data from a demographic surveillance system

 

Methods:

We are conducting a study in Bangladesh as part of the CHAMPS network which will track the causes of under-5 mortality and stillbirths at selected population sites in sub-Saharan Africa and South Asia.  The Bangladesh study will involve epidemiologic surveillance of under-5 deaths and stillbirths utilizing MITS, laboratory diagnostics including conventional and advanced histopathology and molecular screening of various pathogens, verbal autopsy, and extraction of available clinical and demographic data.